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Amino Onko HP
Amino Onko HP

Amino Onko HP

Incl. VAT

Formulation

Presentation: 100 ml infusion concentrate

Composition: N-Acetyl-L-Tyrosine, Aspartic Acid, Glycine, L-Isoleucine, L-Leucine, L-Lysine HCl, L-Phenylalanine, Taurine, L-Valine, Water for Injection q.s.

Prescription status: Prescription only

Storage: Store at room temperature

Shelf life: 1 year after manufacture

After completing your order, you will receive a link through which you can securely upload your prescription.
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PRODUCT INFORMATION

Composition:

  • N-Acetyl-L-tyrosine 1000 mg
  • Aspartic acid 1000 mg
  • Glycine 1000 mg
  • L-isoleucine 1000 mg
  • L-leucine 1000 mg
  • L-lysine HCl 1000 mg
  • L-phenylalanine 1000 mg
  • Taurine 1000 mg
  • L-valine 1000 mg
  • Water for injection to 100 ml

Administration: i.v., always prepare the infusion solution freshly, dilute in 250 ml of 0.9% NaCl 

Infusion set: Intrafix © Air P 

Duration of infusion: approx. 45 minutes 

Therapy interval: 1-2 times per week, based on the patient's health status 

Duration of treatment: 4-8 weeks, based on the patient's health status 

Storage: 15–25°C 

Shelf life: 1 year after manufacture

Side effects High doses of amino acids may cause vein irritation, therefore ensure stable venous access 

  1. Sleep disturbances possible if the infusion is administered in the afternoon 
THERAPY RECOMMENDATION

Positive effects:

  • L-aspartic acid and the salt L-aspartate act as neurotransmitters and are involved in ammonia detoxification in urea metabolism.
  • L-leucine, L-isoleucine, L-valine are essential branched-chain amino acids (BCAAs). They lead to considerable protein anabolism and can prevent cachexia. L-leucine is a major activator of mTOR.
  • BCAAs stimulate gluconeogenesis and insulin secretion and are used in liver diseases. BCAAs support leukocyte formation and have antiviral effects.
  • Neurodegeneration: Branched-chain amino acids inhibit the uptake of aromatic amino acids across the blood-brain barrier and promote ammonia detoxification; they are neuroregenerative.
  • For further information, please refer to Mono-Infusions.

Therapy recommendations: There is evidence that the properties of the substances contained in the product may have a positive effect on health disorders of the mentioned indications:

  • as part of complementary cancer therapy
  • in chronic fatigue
  • in case of lack of vitality

New studies show that the accumulation of BCAAs promotes the effector function and anti-tumor immunity of CD8+ T cells by reprogramming glucose metabolism.

Please refer to the literature for new roles of branched-chain amino acid metabolism in cancer.

Contraindications:Do not use in children under 6 years of age. In case of impaired kidney, liver, or heart function, and in case of albumin deficiency, an adjustment of the individual dose is recommended. Patients taking beta-blockers have an increased risk of a decompensated cardiovascular reaction, as beta-blockers inhibit the effect of adrenaline (emergency medical treatment). Patients with a tendency to allergic reactions and/or with diseases based on histamine release (e.g., asthma) should be questioned about known allergens according to the principles of therapeutic due diligence.

Note for doctors and therapists: In principle, the doctor/therapist determines the indication for individual prescriptions. The suggestion is merely a recommendation for a therapy option, whereby the dosage and frequency of application are solely at the discretion of the doctor/therapist. The treating therapist is responsible for the treatment and must individually check and assess the respective application for each patient before starting treatment.
Shipping Information

NATIONAL:

  • Standard shipping: €9.95 incl. VAT
  • Free shipping on orders over €200.00 (does not apply to refrigerated goods and express shipments)
  • Refrigerated and express shipping: €25.95 incl. VAT

Note: If individual products are unavailable, partial deliveries may occur, incurring no additional shipping costs.
Any requested partial deliveries will be charged.

WITHIN THE EU:
For shipments to countries in EU Zone 1, we charge logistics costs of €75.00 (incl. VAT).

For shipments to countries in EU Zone 2, we charge logistics costs of €105.00 (incl. VAT).

THIRD COUNTRIES:
The customer is asked to inquire about the logistics costs incurred for the respective country.
References

We have researched the literature references with the greatest possible care. Nevertheless, we assume no liability for the completeness and topicality of the study information. Many of the therapy options mentioned in the product information are based on findings obtained from animal or human cell cultures, animal experiments, observational studies, and, to a lesser extent, randomized controlled trials (RCTs).
The study situation for complementary medicines is subject to continuous development, which can sometimes lead to different results. We therefore recommend that therapists always carefully review the current study situation before using such preparations.

  1. 1) Stéphanie Chevalier, Aaron Winter, Do patients with advanced cancer have any potential for protein anabolism in response to amino acid therapy?, Curr Opin Clin Nutr Metab Care., 2014, 17(3):213-8
  2. 2) Sharanya Sivanand, Matthew G. Vander Heiden, Emerging Roles for Branched-Chain Amino Acid Metabolism in Cancer, Cancer Cell Volume 37, 2020
  3. 3) Yvonne Bordon, Leucine restriction limits pro-cancer B cell responses, Nat Rev Immunol., 2022, 22(7):408-40
  4. 4) Cheng-Cheng Yao, Rui-Ming Sun, Yi Yang, Hai-Yan Zhou, Zhou-Wenli Meng, Rui Chi, Li-Liang Xia, Ping Ji, Ying-Ying Chen, Guo-Qing Zhang, Hai-Peng Sun, Shun Lu, Chen Yang, Ying Wang, Accumulation of branched-chain amino acids reprograms glucose metabolism in CD8+ T cells with enhanced effector function and anti-tumor response, Cell Rep., 2023, 42(3):112186
  5. 5) Phillip C Calder, Branched-chain amino acids and immunity, J Nutr., 2006, 136(1 Suppl):288S-93S
  6. 6) Daniela Maria Tanase, Emilia Valasciuc, Claudia Florida Costea, Dragos Viorel Scripcariu, Anca Ouatu, Loredana Liliana Hurjui, Claudia Cristina Tarniceriu, Diana Elena Floria, Manuela Ciocoiu, Livia Genoveva Baroi, Mariana Floria, Duality of Branched-Chain Amino Acids in Chronic Cardiovascular Disease: Potential Biomarkers versus Active Pathophysiological Promoters, Nutrients., 2024, 16(12):1972