Skip to product information
L-Carnitine 2 g
L-Carnitine 2 g

L-Carnitine 2 g

Incl. VAT

Formulation

Presentation: 20 ml infusion concentrate

Composition: L-carnitine, citrate-phosphate buffer, water for injection

Prescription status: prescription only

Storage: store at room temperature

Shelf life: 1 year after manufacture

After completing your order, you will receive a link through which you can securely upload your prescription.
Anmeldung erforderlich
Jetzt einloggen Jetzt registrieren
PRODUCT INFORMATION

Composition: 

  • L-carnitine 2000 mg 
  • Citric acid-phosphate buffer 
  • Water for injection to 20 ml 

Administration: i.v., always prepare the infusion solution freshly dilute as a mono-infusion in 100 ml of 0.9% NaCl

Infusion set: Intrafix © Air P 

Infusion duration: 30 minutes 

Therapy interval: once per week, based on the patient's health status 

Duration of treatment: 6 weeks, based on the patient's health status 

Storage: 15–25°C 

Shelf life: 1 year after manufacture

Side effects: unknown 
THERAPY RECOMMENDATION

Positive effects:

  • L-carnitine is an endogenous β-hydroxy-γ-trimethyl-aminobutyric acid. L-carnitine is produced by the body itself from the essential amino acids L-lysine and L-methionine; co-factors required for endogenous synthesis are vitamins C, B3, B6, and iron.
  • L-carnitine-dependent metabolism is, alongside glycolysis, the oldest in evolution. L-carnitine plays a key role in energy metabolism: L-carnitine transports long-chain fatty acids into the mitochondria, improves mitochondrial function, and converts fat into energy. L-carnitine regulates the citric acid cycle and activates glucose utilization.
  • L-carnitine optimizes the energy metabolism of muscles, contributes to muscle mass development, and has an anabolic effect.
  • L-carnitine has a cell membrane-stabilizing effect (erythrocytes, immune cells, cell organelles, mitochondria).
  • Can have an inhibitory effect on lipid peroxidation.
  • Improves insulin sensitivity and glucose utilization.
  • L-carnitine is a peripheral antagonist of thyroid hormone action. It does not alter TSH.
  • L-carnitine inhibits NF-kB and has anti-inflammatory effects.
  • It has neuroprotective and neuroregenerative effects.
  • Increases neurotransmitter metabolism, acetylcholine.
  • L-carnitine has a positive influence on hematopoiesis.
  • It can enhance immune competence.
  • It can improve blood circulation by activating eNOS.
  • Support for weight loss, increased fat burning.
  • Liver cell protection, detoxifying xenobiotics, improved liver detoxification.

Therapy recommendations: There are indications that the properties of the substances contained in the product may have a positive effect on health disorders of the mentioned indications:

  • general prevention
  • for chronic fatigue, exhaustion, reduced performance, and CFS
  • for brain fog and confirmed hyperammonemia
  • adjunct in tumor therapy; cytoprotection, immunostabilizing effect, prevention of neuropathies and CFS; prevention of L-carnitine deficiency also in combination with cannabinoids
  • for acute and chronic infections
  • for neurodegenerative diseases, including Alzheimer's disease
  • for AD(H)D syndrome accompanied by N-acetyl-L-tyrosine
  • L-carnitine deficiency is often present in cardiovascular diseases; L-carnitine is an energy source for the heart muscle
  • for myositis, inflammation of skeletal muscles
  • adjunct in type 2 diabetes mellitus and insulin resistance
  • for hyperthyroidism
  • for circulatory disorders
  • for increased demand, e.g., in athletes
  • adjunct in weight loss, weight management
  • supports the detoxification of fats

Contraindications:Do not use in children under 6 years of age. In case of impaired kidney, liver, or heart function and albumin deficiency, an adjustment of the individual dose is recommended. Patients taking beta-blockers have an increased risk of a decompensated cardiovascular reaction, as beta-blockers inhibit the effect of adrenaline (emergency medical treatment). Patients with a tendency to allergic reactions and/or with diseases based on histamine release (e.g., asthma) should be questioned about known allergens according to the principles of therapeutic due diligence.

Note for doctors and therapists: In principle, the doctor/therapist determines the indication for individual prescriptions. The suggestion is merely a recommendation for a therapy option, whereby the dosage and frequency of application are solely at the discretion of the doctor/therapist. The treating therapist is responsible for the treatment and must individually review and assess the respective application for each patient before starting treatment.
Shipping Information

NATIONAL:

  • Standard shipping: €9.95 incl. VAT
  • Free shipping on orders over €200.00 (does not apply to refrigerated goods and express shipments)
  • Refrigerated and express shipping: €25.95 incl. VAT

Note: If individual products are unavailable, partial deliveries may occur, incurring no additional shipping costs.
Any requested partial deliveries will be charged.

WITHIN THE EU:
For shipments to countries in EU Zone 1, we charge logistics costs of €75.00 (incl. VAT).

For shipments to countries in EU Zone 2, we charge logistics costs of €105.00 (incl. VAT).

THIRD COUNTRIES:
The customer is asked to inquire about the logistics costs incurred for the respective country.
References

We have researched the literature with the greatest possible care. Nevertheless, we assume no liability for the completeness and topicality of the study information. Many of the therapeutic options mentioned in the product information are based on findings obtained from animal or human cell cultures, animal experiments, observational studies, and, to a lesser extent, randomized controlled trials (RCTs). The body of research on complementary medicines is subject to continuous development, which can sometimes lead to different results. We therefore recommend that therapists always carefully review the current research before using such preparations.

1) Roger Fielding, Linda Riede, James P Lugo, Aouatef Bellamine, l-Carnitine Supplementation in Recovery after Exercise, Nutrients, 2018, 13;10(3):349
2) Antonio Gnoni, Serena Longo, Gabriele V Gnoni, Anna M Giudetti, Carnitine in Human Muscle Bioenergetics: Can Carnitine Supplementation Improve Physical Exercise?, Molecules, 2020, 25(1):182
3) Juan Mielgo-Ayuso, Laura Pietrantonio, Aitor Viribay, Julio Calleja-González, Jerónimo González-Bernal, Diego Fernández-Lázaro, Effect of Acute and Chronic Oral l-Carnitine Supplementation on Exercise Performance Based on the Exercise Intensity: A Systematic Review, Nutrients, 2021, 13(12):4359
4) Larissa Espindola da Silva, Mariana Pacheco de Oliveira, Mariella Reinol da Silva, Jéssica da Silva Abel, Gisele Tartari, Maiara de Aguiar da Costa, Cinara Ludvig Gonçalves, Gislaine Tezza Rezin, L-carnitine and Acetyl-L Carnitine: A Possibility for Treating Alterations Induced by Obesity in the Central Nervous System, Neurochem Res., 2023, 48(11):3316-3326
5) I S Al-Dhuayan, Biomedical role of L-carnitine in several organ systems, cellular tissues, and COVID-19, Braz J Biol., 2023, 9:82:e267633
6) L R Wiseman, R N Brogden, Propionyl-L-carnitine, Drugs Aging, 1998, 12(3):243-8
7) Graziela S Ribas, Carmen R Vargas, Moacir Wajner, L-carnitine supplementation as a potential antioxidant therapy for inherited neurometabolic disorders, Gene, 2014, 533(2):469-76
8) Zongliang Lu, Li Wang, Zhenyu Huo, Na Li, Ning Tong, Feifei Chong, Jie Liu, Yaowen Zhang, Hongxia Xu, l-Carnitine relieves cachexia-related skeletal muscle fibrosis by inducing deltex E3 ubiquitin ligase 3L to negatively regulate the Runx2/COL1A1 axis, J Cachexia Sarcopenia Muscle, 2024, 15(5):1953-1964
9) S Ahmad, L-carnitine in dialysis patients, Semin Dial, 2001, 14(3):209-17
10) Roberto Ferrari, E Merli, G Cicchitelli, D Mele, A Fucili, C Ceconi, Therapeutic effects of L-carnitine and propionyl-L-carnitine on cardiovascular diseases: a review, Ann N Y Acid Sci., 2004, 1033:79-91
11) S Susan Hedayati, Dialysis-related carnitine disorder, Semin Dial, 2006, 19(4):323-8
12) Jun Ho Kim, Jeong Hoon Pan, Eui Seop Lee, Young Jun Kim, L-Carnitine enhances exercise endurance capacity by promoting muscle oxidative metabolism in mice, Biochem Biophys Res Commun, 2015, 464(2):568-73
13) Gamze E Orer, Nevin A Guzel, The effects of acute L-carnitine supplementation on endurance performance of athletes, J Strength Cond Res, 2014, 28(2):514-9
14) M Pooyandjoo, M Nouhi, S Shab-Bidar, K Djafarian, A Olyaeemanesh, The effect of (L-)carnitine on weight loss in adults: a systematic review and meta-analysis of randomized controlled trials, Obes Rev, 2016, 17(10):970-6
15) James J DiNicolantonio, Carl J Lavie, Hassan Fares, Arthur R Menezes, James H O'Keefe, L-carnitine in the secondary prevention of cardiovascular disease: systematic review and meta-analysis, Mayo Clin Proc., 2013, 88(6):544-51
16) Amin Mirrafiei, Ahmad Jayedi, Sakineh Shab-Bidar, The Effects of L-Carnitine Supplementation on Weight Loss, Glycemic Control, and Cardiovascular Risk Factors in Patients With Type 2 Diabetes: A Systematic Review and Dose-response Meta-Analysis of Randomized Controlled Trials, Clin Ther, 2024, 46(5):404-410
17) Dong-Dong Wang, Yi-Zhen Mao, Su-Mei He, Yang Yang, Xiao Chen, Quantitative efficacy of L-carnitine supplementation on glycemic control in type 2 diabetes mellitus patients, Expert Rev Clin Pharmacol, 2021, 14(7):919-926
18) Youn-Soo Cha, Effects of L-carnitine on obesity, diabetes, and as an ergogenic aid, Asia Pac J Clin Nutr, 2008
19) Zhong-Yu Wang, Ying-Yi Liu, Guo-Hui Liu, Hai-Bin Lu 3, Cui-Ying Mao, l-Carnitine and heart disease, Life Sci., 2018, 194:88-97
20) María M Adeva-Andany, Isabel Calvo-Castro, Carlos Fernández-Fernández 1, Cristóbal Donapetry-García, Ana María Pedre-Piñeiro, Significance of l-carnitine for human health, IUBMB Life, 2017, 69(8):578-594
21) Nasir Talenezhad, Mohammad Mohammadi, Nahid Ramezani-Jolfaie, Hassan Mozaffari-Khosravi, Amin Salehi-Abargouei, Effects of l-carnitine supplementation on weight loss and body composition: A systematic review and meta-analysis of 37 randomized controlled clinical trials with dose-response analysis, Clin Nutr ESPEN, 2020, 37:9-23
22) Moein Askarpour, Amir Hadi, Maryam Miraghajani, Michael E Symonds, Ali Sheikhi, Ehsan Ghaedi, Beneficial effects of l-carnitine supplementation for weight management in overweight and obese adults: An updated systematic review and dose-response meta-analysis of randomized controlled trials, Pharmacol Res., 2020, 151:104554
23) Gröber U, Holzhauer P, Kisters K, Holick MF, Adamietz IA, Micronutrients in Oncological Intervention, Nutrients.2016 Mar 12;8(3):163.