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NAD+ 125 mg
NAD+ 125 mg

NAD+ 125 mg

Incl. VAT

Prescription

Presentation: 1 injection vial containing dry substance (lyophilisate) + 10 ml solvent

Composition: Nicotinamide adenine dinucleotide (NAD+) 125 mg

Prescription status: prescription-only

Storage: keep refrigerated

After completing your order, you will receive a link through which you can securely upload your prescription.
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PRODUCT INFORMATION

Zusammensetzung:

  • Nicotinamid-Adenin-Dinukleotid (NAD+) 125 mg
  • Lyophilisat
  • 10 ml Lösungsmittel zur Rekonstitution

Applikation: Das Lyophilisat zunächst mit den beiliegenden 10 ml Lösungsmittel rekonstituieren und anschließend in 250 ml oder 500 ml Ringer- bzw. Ringer-Lactat-Lösung verdünnen. Die Infusionslösung stets frisch zubereiten.

Infusionsbesteck: Intrafix® Air P

Dauer der Infusion: mindestens ca. 2 bis 2,5 Stunden

Therapieintervall: 1–2 x pro Woche, abhängig vom individuellen Gesundheitszustand des Patienten

Behandlungsdauer: ca. 6–8 Wochen, abhängig vom individuellen Gesundheitszustand

Lagerung: Kühlware

Hinweis zur Anwendung: Bei der ersten NAD+-Infusion sollte mit der niedrigsten Konzentration begonnen werden. Die Infusionsgeschwindigkeit wird zu Beginn langsam gewählt und kann bei guter Verträglichkeit entsprechend angepasst werden.
THERAPY RECOMMENDATION

NAD+ and Cellular Metabolism

Nicotinamide adenine dinucleotide, or NAD+ for short, is an endogenous coenzyme involved in numerous cellular metabolic processes. NAD+ plays a key role, among others, in mitochondrial energy production as well as in cellular function and repair processes.

NAD+ levels in the body may decrease with age. Accordingly, NAD+ is increasingly being focused on, particularly in connection with mitochondrial processes, energy balance, cell regeneration, and cognitive functions.

Possible areas of application within individual treatment concepts may include:

  • Exhaustion and chronic fatigue
  • Regeneration and convalescence
  • Support for mitochondrial dysfunctions
  • Concentration and memory problems
  • Brain fog
  • Regeneration after physical exertion
  • Complementary concepts in the field of healthy aging and cellular health

The individual determination of indications, as well as the dosage and frequency of administration, is the responsibility of the treating physician or therapist.

Contraindications and special precautions:
Do not use as part of cancer therapy. In cases of impaired kidney, liver, or heart function, as well as in cases of albumin deficiency, an individual dose adjustment should be considered. Please refer to the product information for further contraindications, possible side effects, and directions for use.

Information for physicians and therapists:
For individual prescriptions, the treating physician or therapist determines the indication individually. The stated areas of application serve exclusively as guidance for possible treatment options. The suitability of the application must be assessed individually for each patient before starting treatment.
Shipping Information

NATIONAL:

  • Standard shipping: €9.95 incl. VAT
  • Free shipping on orders over €200.00 (does not apply to refrigerated goods and express shipments)
  • Refrigerated and express shipping: €25.95 incl. VAT

Note: If individual products are unavailable, partial deliveries may occur, incurring no additional shipping costs.
Any requested partial deliveries will be charged.

WITHIN THE EU:
For shipments to countries in EU Zone 1, we charge logistics costs of €75.00 (incl. VAT).

For shipments to countries in EU Zone 2, we charge logistics costs of €105.00 (incl. VAT).

THIRD COUNTRIES:
The customer is asked to inquire about the logistics costs incurred for the respective country.
References

The bibliographic information was researched by us with the utmost care. Nevertheless, we assume no liability for the completeness and timeliness of the study information. Many of the treatment options mentioned in the product information are based on findings obtained from animal or human cell cultures, animal studies, observational studies, and to a lesser extent, randomized controlled trials (RCTs).
The evidence base for complementary medicines is continuously evolving, which can partly lead to different results. We therefore recommend that practitioners always carefully review the current evidence before using such preparations.

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3) Gröber, U. NAD+ – ein alter Bekannter aus den Anfängen der Orthomolekularen Medizin, OM – Zs. f. Orthomol. 2023; 21: 36–41,

4) Gröber, U. 2008. Orthomolekulare Medizin. Ein Leitfaden für Apotheker und Ärzte

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6) Böhm U, Muss C, Pfisterer M. Rationelle Diagnostik in der Orthomolekularen Medizin – Optimale Therapie durch individuelle Diagnostik. Hippokrates, 2004

7) Burgerstein, L. 2023. Handbuch der Nährstoffe

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9) Schmidt N, Schimdt E. Mikronährstoff-Therapie. Urban & Fischer Verlag, 2022

10) Schmidbauer C, Hofstätter G. Mikronährstoff-Coach – Das große BIOGENA-Kompendium der Nährstoffe. Verlagshaus der Ärzte, 2018

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13) Meyer R. Chronisch gesund – Prinzipien einer Gesundheitspraxis, 2010

14) Schilling F. Long-Covid und Post-Vac – Handbuch für Spike-Geschädigte. Tredition, 2022

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19) Dehhaghi M, Panahi HKS, Kavyani B, Heng B, Tan V, Braidy N, Guillemin GJ. The Role of Kynurenine Pathway and NAD+ Metabolism in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. Aging Dis.2022 Jun 1;13(3):698-711.

20) Isman A, Nyquist A, Strecker B, Harinath G, Lee V, Zhang X, Zalzala S. Low-dose naltrexone and NAD+ for the treatment of patients with persistent fatigue symptoms after COVID-19, Brain Behav Immun Health.2024 Feb 1:36:100733.

21) Barnish M, Sheikh M, Scholey A. Nutrient Therapy for the Improvement of Fatigue Symptoms Nutrients. 2023 Apr 30;15(9):2154.

22) Blanco-Vaca F, Rotllan N, Canyelles M, Mauricio D, Escolà-Gil JC, Julve J. NAD+-Increasing Strategies to Improve Cardiometabolic Health? Front Endocrinol (Lausanne). 2022 Jan 31:12:815565.

23) Abdellatif M, Sedej S, Kroemer G. NAD+ Metabolism in Cardiac Health, Aging, and Disease, Circulation.2021 Nov 30;144(22):1795-1817.

24) Alghamdi M, Braidy N. Supplementation with NAD+ Precursors for Treating Alzheimer's Disease: A Metabolic Approach, J Alzheimers Dis.2024;101(s1):S467-S477.

25) Guo C, Huang Q, Wang Y, Yao Y, Li J, Chen J, Wu M, Zhang Z, E M, Qi H, Ji P, Liu Q, Zhao D, Su H, Qi W, Li X., Therapeutic application of natural products: NAD+ metabolism as potential target, Phytomedicine.2023 Jun:114:154768.

26) Shi Y, Peng J, Liu M, Qi X, Li S, Li Q, Jiang Q, Zheng L, Xu J, Zhao Y, Zhang Y. Nicotinamide mononucleotide enhances fracture healing by promoting skeletal stem cell proliferation, Theranostics.2024 Sep 16;14(15):5999-6015.

27) Gibril BAA, Xiong X, Chai X, Xu Q, Gong J, Xu J. Unlocking the Nexus of Sirtuins: A Comprehensive Review of Their Role in Skeletal Muscle Metabolism, Development, and Disorders, Int J Biol Sci.2024 Jun 3;20(8):3219-3235.

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